PXD050886-2

PXD050886 is an original dataset announced via ProteomeXchange.

Title	Bacterial community structure and metabolomic pathways in yak milk and cattle-yak milk during refrigeration: analysis of interspecific differences in dairy spoilage
Description	Raw milk usually needs to be refrigerated at 4℃ before production, and microbial contamination during this process can cause spoilage of refrigerated raw milk. However, there is currently almost no research on plateau characteristic milk (yak milk and cattle-yak milk) (YM and CYM). In this study, significant differences in bacterial communities and their succession patterns were found between YM and CYM during 4℃ refrigeration, while Lactococcus, Pseudomonas, and Serratia revealed significant differences between the two groups of milk by Ancom2 analysis. And the microbial community in CYM exhibits higher network complexity and tighter interactions. The enzymes exhibiting stronger correlations identified in YM are more abundant than those in CYM predicted by PICRUSt2. Through metabolomics methods, the metabolome profiles between CYM and YM during refrigeration were significantly different. With the extension of storage time, the relative abundances of lipids and lipid-like molecules, and organic nitrogen compounds were decreased, the relative abundances of organic acids and derivatives was increased (YM is more obvious than CYM). Moreover, 8 metabolites gradually increases with the extension of storage time, and has a good correlation with Psychropliles growth. These metabolites have the potential to serve as markers of plateau characteristic milk deterioration. The results will provide a theoretical basis for improving the quality and safety of plateau characteristic milk and its products.
HostingRepository	iProX
AnnounceDate	2024-03-22
AnnouncementXML	Submission_2024-10-15_01:27:22.546.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sixue Yang
SpeciesList	scientific name: Bos taurus; NCBI TaxID: 9913;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-21 23:49:12	ID requested
1	2024-03-21 23:50:18	announced
⏵ 2	2024-10-15 01:27:23	announced	2024-10-15: Update information.

Li H, Wang H, Gao Y, Zhao X, Liang J, Pei L, Yao Y, Tang D, Bacterial community structure and metabolomic profiles of yak milk and cattle-yak milk during refrigeration in Gannan region: Analysis of interspecific differences in milk spoilage. Food Chem, 463(Pt 1):141022(2025) [pubmed]

submitter keyword: yak milk, cattle-yak milk, refrigeration, bacterial community succession, metabolite

Hongqiang Li
contact affiliation	College of Animal Science and Technology, Gansu Agricultural University
contact email	lhq136531597@163.com
lab head
Sixue Yang
contact affiliation	College of Animal Science and Technology, Gansu Agricultural University
contact email	yangsixue1997@163.com
dataset submitter

iProX dataset URI