PXD050873-1

PXD050873 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	superoxide dismutase 1 (SOD1) trimer interactome from mouse brain, spinal cord, and muscle tissues
Description	In this work, we aimed to discover the protein binding partners of SOD1 trimers in brain, spinal cord, and skeletal muscle of mice tissue lysate.
HostingRepository	PRIDE
AnnounceDate	2025-10-06
AnnouncementXML	Submission_2025-10-05_17:55:36.031.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Esther Choi
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue
Instrument	5800 TOF/TOF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-21 14:39:14	ID requested
⏵ 1	2025-10-05 17:55:37	announced

Publication List

10.1016/j.str.2024.08.002;
Choi ES, Hnath B, Sha CM, Dokholyan NV, Unveiling the double-edged sword: SOD1 trimers possess tissue-selective toxicity and bind septin-7 in motor neuron-like cells. Structure, 32(10):1776-1792.e5(2024) [pubmed]

10.1016/j.str.2024.08.002;

Choi ES, Hnath B, Sha CM, Dokholyan NV, Unveiling the double-edged sword: SOD1 trimers possess tissue-selective toxicity and bind septin-7 in motor neuron-like cells. Structure, 32(10):1776-1792.e5(2024) [pubmed]

Keyword List

submitter keyword: oligomers, interactome,SOD1

submitter keyword: oligomers, interactome,SOD1

Contact List

Nikolay V Dokholyan
contact affiliation	Department of Pharmacology, Penn State College of Medicine, Hershey, PA, USA
contact email	nxd33@psu.edu
lab head
Esther Choi
contact affiliation	Penn State College of Medicine
contact email	euc504@psu.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD050873
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD050873

PRIDE project URI

Repository Record List

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