PXD050833-1

PXD050833 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Lysyl Oxidase Mediated Collagen Cross-linking in Pancreatic Cancer
Description	Bottom up proteomics, cross-linked amino acid analysis, and cross-linked peptide analysis were performed on eight PDAC tumor samples and paired adjacent non-tumor samples.
HostingRepository	PRIDE
AnnounceDate	2025-08-28
AnnouncementXML	Submission_2025-08-28_14:35:30.270.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kirk Hansen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	2-pyrrolidone-5-carboxylic acid (Gln); acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-20 16:25:23	ID requested
⏵ 1	2025-08-28 14:35:31	announced

Publication List

10.1021/acs.biochem.5c00125;
Barrett A, Maslanka MD, Darula Z, McCabe MC, Saviola AJ, Schmitt LR, Weaver V, Pitts TM, Messersmith WA, Hansen KC, Pancreatic Cancer Progression Involves Increased Lysyl Oxidase-Mediated Collagen Cross-Links as Part of the Desmoplastic Reaction. Biochemistry, 64(16):3515-3525(2025) [pubmed]

10.1021/acs.biochem.5c00125;

Barrett A, Maslanka MD, Darula Z, McCabe MC, Saviola AJ, Schmitt LR, Weaver V, Pitts TM, Messersmith WA, Hansen KC, Pancreatic Cancer Progression Involves Increased Lysyl Oxidase-Mediated Collagen Cross-Links as Part of the Desmoplastic Reaction. Biochemistry, 64(16):3515-3525(2025) [pubmed]

Keyword List

submitter keyword: Collagen, Lysyl hydroxylase, xAAA, lysyl oxidase, N-telo peptide, PLOD, LOX,Cross-linked peptide, NTX, PDAC

submitter keyword: Collagen, Lysyl hydroxylase, xAAA, lysyl oxidase, N-telo peptide, PLOD, LOX,Cross-linked peptide, NTX, PDAC

Contact List

Kirk Hansen
contact affiliation	University of Colorado Anschutz Medical Campus - Department of Biochemistry and Molecular Genetics
contact email	kirk.hansen@cuanschutz.edu
lab head
Kirk Hansen
contact affiliation	Univeristy of Colorado
contact email	kirk.hansen@cuanschutz.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD050833
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD050833

PRIDE project URI

Repository Record List

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