PXD050791-1
PXD050791 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Substrate and Functional Characterization of the Lysine Acetyltransferase and Deacetylase in Mycobacteria |
| Description | We utilized the non-pathogenic M. smegmatis strain as a model and systematically investigated the dynamic proteome changes in response to the overexpressing of MsKat/MtCobB in mycobacteria. After that, the quantitative mass spectrometric method was utilized and showed that the AMP-dependent synthetase, Citrate synthase, ATP-dependent specificity component of the Clp protease, and ATP-dependent DNA/RNA helicases were identified to be the substrates of MsKat. |
| HostingRepository | iProX |
| AnnounceDate | 2024-03-20 |
| AnnouncementXML | Submission_2024-03-19_23:35:45.150.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Junyu Xu |
| SpeciesList | scientific name: Mycolicibacterium smegmatis MC2 51; NCBI TaxID: 1445611; |
| ModificationList | acetylated residue |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-03-19 23:35:00 | ID requested | |
| ⏵ 1 | 2024-03-19 23:35:45 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Mycobacteria, Acetylome, Acetyltransferase, Deacetylase |
Contact List
| Minjia Tan | |
|---|---|
| contact affiliation | Chinese Academy of Sciences Shanghai Institute of Materia Medica |
| contact email | mjtan@simm.ac.cn |
| lab head | |
| Junyu Xu | |
| contact affiliation | Chinese Academy of Sciences Shanghai Institute of Materia Medica |
| contact email | XJY89089@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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