PXD050764 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The proteins of PK-15 cells infected with porcine parvovirus were identified and quantitatively analyzed by TMT labeling at 6 h and 36 h after infection, and the results were analyzed by gene ontology, KEGG and PPI bioinformatics. |
Description | In this project, TMT labeling quantitative proteomics technology was used to carry out the research, and a total of 4769 proteins were identified. The differentially expressed proteins were screened according to the criteria that the expression multiple changed more than 1.5 times (up-regulated more than 1.5 times or down-regulated less than 0.67 times) and P value < 0.05. The differentially expressed proteins were screened according to the criteria that the expression multiple changed more than 1.5 times (up-regulated more than 1.5 times or down-regulated less than 0.67). Among them, taking 6h VS 36h as an example, 120 differentially expressed proteins were up-regulated and 67 down-regulated. Through GO enrichment and KEGG pathway analysis, it was found that these differentially expressed proteins were mainly involved in important biological processes such as regulation of localization, cellular homeostasis, regulation of ion transmembrane transport, cytoskeleton organization and negative regulation of lymphocyte mediated immunity, and mainly involved in the regulation of important KEGG metabolic pathways such as Legionellosis, Steroid biosynthesis, Pentose and glucuronate interconversions, Adherens junction and Endocytosis. |
HostingRepository | PRIDE |
AnnounceDate | 2024-04-25 |
AnnouncementXML | Submission_2024-04-25_01:47:21.206.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Raymond Xu |
SpeciesList | scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-03-19 05:48:04 | ID requested | |
⏵ 1 | 2024-04-25 01:47:21 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: PPI, Proteomics, KEGG, PK-15 cells, gene ontology,Porcine parvovirus |
Contact List
Wei Zhanyong |
contact affiliation | College of Veterinary Medicine, Henan Agricultural University |
contact email | weizhanyong@henau.edu.cn |
lab head | |
Raymond Xu |
contact affiliation | college of veterinary medicine, henan agricultural university |
contact email | Boram507@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD050764
- Label: PRIDE project
- Name: The proteins of PK-15 cells infected with porcine parvovirus were identified and quantitatively analyzed by TMT labeling at 6 h and 36 h after infection, and the results were analyzed by gene ontology, KEGG and PPI bioinformatics.