PXD050701-2
PXD050701 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic of control and FBL knockdown C4-2 cells |
| Description | We employed a quantitative proteomics approach to compare the protein expression levels between control and FBL knockdown C4-2 cells, revealing expression levels of some proteins which have decreased mRNA half-life. |
| HostingRepository | iProX |
| AnnounceDate | 2024-03-17 |
| AnnouncementXML | Submission_2025-08-28_23:50:42.217.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yanqiang Li |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ; Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-03-17 20:58:13 | ID requested | |
| 1 | 2024-07-31 19:39:42 | announced | |
| ⏵ 2 | 2025-08-28 23:52:54 | announced | 2025-08-29: Add info. |
Publication List
| Li Y, Yi Y, Gao X, Wang X, Zhao D, Wang R, Zhang LS, Gao B, Zhang Y, Zhang L, Cao Q, Chen K, 2'-O-methylation at internal sites on mRNA promotes mRNA stability. Mol Cell, 84(12):2320-2336.e6(2024) [pubmed] |
Keyword List
| submitter keyword: FBL, 2′-O methylation, protein |
Contact List
| Kaifu Chen | |
|---|---|
| contact affiliation | Boston Childrens Hospital |
| contact email | Kaifu.Chen@childrens.harvard.edu |
| lab head | |
| Yanqiang Li | |
| contact affiliation | Boston Childrens Hospital |
| contact email | Yanqiang.Li@childrens.harvard.edu |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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