PXD050687-1

PXD050687 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Quantitative proteomics analysis of cumulus cells from the young and old mice
Description	Cumulus cells from the young and old mice were subjected to the TMT6 labeling, HP-RP fractionation, and LC-MS/MS analysis. Cumulus cells surrounding 375 oocytes were collected in each of the three biological replicates. Raw files were analyzed using MaxQuant software.
HostingRepository	PRIDE
AnnounceDate	2025-08-25
AnnouncementXML	Submission_2025-08-24_17:02:40.120.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yueshuai Guo
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-16 20:54:24	ID requested
⏵ 1	2025-08-24 17:02:40	announced

Publication List

10.1111/cpr.70014;
Shi L, Wang H, Zhu S, Chen M, Guo X, Wang Q, Gu L, Multi-Omics Reveal the Metabolic Changes in Cumulus Cells During Aging. Cell Prolif, 58(8):e70014(2025) [pubmed]

10.1111/cpr.70014;

Shi L, Wang H, Zhu S, Chen M, Guo X, Wang Q, Gu L, Multi-Omics Reveal the Metabolic Changes in Cumulus Cells During Aging. Cell Prolif, 58(8):e70014(2025) [pubmed]

Keyword List

submitter keyword: mouse,LC-MS/MS,TMT,cumulus cells

submitter keyword: mouse,LC-MS/MS,TMT,cumulus cells

Contact List

Xuejiang Guo
contact affiliation	State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing 211166, China
contact email	guo_xuejiang@njmu.edu.cn
lab head
Yueshuai Guo
contact affiliation	Nanjing Medical University
contact email	gys_706@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD050687
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD050687

PRIDE project URI

Repository Record List

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