<<< Full experiment listing

PXD050636-1

PXD050636 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePalmitoylation licenses RIPK1 cytotoxicity in the TNF pathway
DescriptionWe identified S-palmitoylation as a licensing modification for RIPK1 kinase activity in the TNF pathway. We found that DHHC5 palmitoylates RIPK1 at Cys257 residue, a process dependent on K63-linked ubiquitination of RIPK1, in response to TNF stimulation.
HostingRepositoryiProX
AnnounceDate2024-03-15
AnnouncementXMLSubmission_2024-03-14_19:09:18.284.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBing Shan
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-03-14 19:08:56ID requested
12024-03-14 19:09:18announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: palmitoylation, RIPK1,TNF
Contact List
Daichao Xu
contact affiliationShanghai Institute of Organic Chemistry, Chinese Academy of Sciences
contact emailxudaichao@sioc.ac.cn
lab head
Bing Shan
contact affiliationShanghai Institute of Organic Chemistry, Chinese Academy of Sciences
contact emailshanbing@sioc.ac.cn
dataset submitter
Full Dataset Link List
iProX dataset URI