PXD050636-1
PXD050636 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Palmitoylation licenses RIPK1 cytotoxicity in the TNF pathway |
| Description | We identified S-palmitoylation as a licensing modification for RIPK1 kinase activity in the TNF pathway. We found that DHHC5 palmitoylates RIPK1 at Cys257 residue, a process dependent on K63-linked ubiquitination of RIPK1, in response to TNF stimulation. |
| HostingRepository | iProX |
| AnnounceDate | 2024-03-15 |
| AnnouncementXML | Submission_2024-03-14_19:09:18.284.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Bing Shan |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-03-14 19:08:56 | ID requested | |
| ⏵ 1 | 2024-03-14 19:09:18 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: palmitoylation, RIPK1,TNF |
Contact List
| Daichao Xu | |
|---|---|
| contact affiliation | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences |
| contact email | xudaichao@sioc.ac.cn |
| lab head | |
| Bing Shan | |
| contact affiliation | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences |
| contact email | shanbing@sioc.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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