PXD050580 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Protease Regulation by Subtrate O-Glycosylation |
Description | In this study, we systematically assessed the fine-tuning of limited proteolysis in the extracellular space by glycosylation, one of the most widely observed PTMs, using cells, and applying the Terminal Amine Labeling of Substrates (TAILS) approach, a quantitative proteomics workflow for the system-wide assessment of protein N termini and protease cleavage events in complex biological samples |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:54:36.486.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Elizabeta Madzharova |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-03-13 02:57:35 | ID requested | |
1 | 2024-08-10 16:11:33 | announced | |
⏵ 2 | 2024-10-22 06:54:38 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1002/pro.5128; |
Madzharova E, Sabino F, Kalogeropoulos K, Francavilla C, Auf dem Keller U, Substrate O-glycosylation actively regulates extracellular proteolysis. Protein Sci, 33(8):e5128(2024) [pubmed] |
Keyword List
submitter keyword: PTMs,proteomics, degradomics |
Contact List
Chiara Francavilla |
contact affiliation | 1Department of Biotechnology and Biomedicine, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark |
contact email | chiafra@dtu.dk |
lab head | |
Elizabeta Madzharova |
contact affiliation | Technical University of Denmark |
contact email | elimad@dtu.dk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD050580 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD050580
- Label: PRIDE project
- Name: Protease Regulation by Subtrate O-Glycosylation