PXD050564-1

PXD050564 is an original dataset announced via ProteomeXchange.

Title	Characterization of the SFPQ-forming meshwork condensate for multi-dimensional gene regulation and its implications in autism spectrum disorder
Description	To comprehensively identify the entire gene expression regulatory complex associated with SFPQ in vivo, we conducted purification of biotinylated proteins within the LLPS structure and subsequently characterized them using mass spectrometry. HEK 293T cells expressing TurboID-SFPQ and cells expressing SFPQ lacking TurboID as a negative control were both labeled with 500 μM biotin for 10 minutes, and the cell lysates were subjected to pull-down using streptavidin beads for purification.
HostingRepository	jPOST
AnnounceDate	2026-06-13
AnnouncementXML	Submission_2026-06-12_08:00:04.579.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Koshi Imami
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; unknown modification
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-12 19:31:30	ID requested
⏵ 1	2026-06-12 08:00:05	announced

Dataset with its publication pending

submitter keyword: TurboID, Sfpq, LLPS

Akihide Takeuchi
lab head
Koshi Imami
contact affiliation	RIKEN
dataset submitter

jPOST dataset URI

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