PXD050509-1

PXD050509 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of host proteins implicated in Hepatitis B virus genome packaging
Description	We isolated pgRNA and characterized its protein interactome in cells transfected with packaging competent and packaging incompetent HBV plasmids to identify proteins potentially playing a role in viral packaging. We identified over 250 proteins preferentially associated with pgRNA from the packaging competent version of the virus. These included proteins known to support capsid formation, enhance viral gene expression, catalyze nucleocapsid dephosphorylation, and bind to N6-methylations on the viral genome.
HostingRepository	MassIVE
AnnounceDate	2024-06-12
AnnouncementXML	Submission_2024-06-12_07:49:59.789.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Isabella Whitworth
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; scientific name: Hepatitis B virus; NCBI TaxID: 10407;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-10 18:02:55	ID requested
⏵ 1	2024-06-12 07:50:00	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: interactomics, RNA binding proteins, Hepatitis B Virus, viral packaging, HyPR-MS, RNA-protein interactions, host-pathogen interactions, pregenomic RNA

submitter keyword: interactomics, RNA binding proteins, Hepatitis B Virus, viral packaging, HyPR-MS, RNA-protein interactions, host-pathogen interactions, pregenomic RNA

Contact List

Lloyd Smith
contact affiliation	University of Wisconsin-Madison
contact email	smith@chem.wisc.edu
lab head
Isabella Whitworth
contact affiliation	University of Wisconsin-Madison
contact email	iwhitworth@wisc.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000094286/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000094286/