PXD050403-1

PXD050403 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Immuno-Oncologic Profiling by Stage-Dependent Transcriptome and Proteome Analyses of Spontaneously Regressing Canine Cutaneous Histiocytoma
Description	Canine cutaneous histiocytoma (CCH) is a tumor originating from dermal Langerhans cells, especially affecting young dogs. The common spontaneous regression of CCH makes it an interesting model in comparative oncology research. Here, we asked which specific immuno-oncological dynamics underlie spontaneous regression of CCH on mRNA and protein levels. QuantSeq 3' mRNA sequencing with functional overrepresentation analysis and an nCounter RNA hybridization assay were employed on CCH samples representing three different tumor stages. Additionally, samples were subjected to matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI).
HostingRepository	MassIVE
AnnounceDate	2024-03-25
AnnouncementXML	Submission_2024-03-25_02:16:59.347.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Benjamin-Florian Hempel
SpeciesList	scientific name: Canis lupus familiaris; common name: dog; NCBI TaxID: 9615;
ModificationList	No PTMs are included in the dataset
Instrument	ultrafleXtreme; Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-06 06:04:22	ID requested
⏵ 1	2024-03-25 02:16:59	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Canine Cutaneous Histiocytoma, Mass Spectrometry Imaging, Proteomics

submitter keyword: Canine Cutaneous Histiocytoma, Mass Spectrometry Imaging, Proteomics

Contact List

Benjamin-Florian Hempel
contact affiliation	Freie University Berlin
contact email	benjamin.hempel@fu-berlin.de
lab head
Benjamin-Florian Hempel
contact affiliation	Freie University Berlin
contact email	benjamin.hempel@fu-berlin.de
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000094245/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000094245/