PXD050121-2

PXD050121 is an original dataset announced via ProteomeXchange.

Title	Sirtuin 5-mediated desuccinylation of ALDH2 alleviates mitochondrial oxidative stress following acetaminophen-induced acute liver injury
Description	WT mice and SIRT5 knockout mice were injected with APAP by intraperitoneal injection, and liver tissue specimens were taken 24 hours later for protein succinylation modification histology analysis
HostingRepository	iProX
AnnounceDate	2024-02-24
AnnouncementXML	Submission_2024-10-12_00:00:49.543.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qiwen Yu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-25 21:44:14	ID requested
1	2024-02-25 21:44:47	announced
⏵ 2	2024-10-12 00:00:50	announced	2024-10-12: Update information.

Yu Q, Zhang J, Li J, Song Y, Pan J, Mei C, Cui M, He Q, Wang H, Li H, Cheng B, Zhang Y, Guo W, Zhu C, Chen S, Sirtuin 5-Mediated Desuccinylation of ALDH2 Alleviates Mitochondrial Oxidative Stress Following Acetaminophen-Induced Acute Liver Injury. Adv Sci (Weinh), 11(39):e2402710(2024) [pubmed]

submitter keyword: SIRT5, Acute liver injury, ALDH2, Succinylation, Mitochondrial oxidative stress

Sanyang Chen
contact affiliation	First Affiliated Hospital of Zhengzhou University
contact email	chensy0521@163.com
lab head
Qiwen Yu
contact affiliation	First Affiliated Hospital of Zhengzhou University
contact email	yuqiwen926@163.com
dataset submitter

iProX dataset URI