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PXD050089-1

PXD050089 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteomics confirms CpKRS is over-expressed in genetically modified strain.
DescriptionC. parvum was genetically modified to over-express CpKRS. The CpTK locus was replaced wit a cassette containing CpKRS and the dual reporter-selection marker, Nluc-NeoR, driven by the CpEnolase promoter. Quantitative proteomics analysis confirms over-expression of CpKRS and similar significantly increased expression of Nluc-NeoR.
HostingRepositoryPRIDE
AnnounceDate2024-07-05
AnnouncementXMLSubmission_2024-07-05_06:12:03.921.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMichele Tinti
SpeciesList scientific name: Cryptosporidium parvum Iowa II; NCBI TaxID: 353152;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-23 08:41:39ID requested
12024-07-05 06:12:04announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: TMT, Cryptosporidium, lysyl-tRNA synthetase,cryptosporidiosis
Contact List
Mattie Pawlowic
contact affiliationWellcome Centre for Anti-Infectives Research, Division ofBiological Chemistry and Drug Discovery
contact emailm.c.pawlowic@dundee.ac.uk
lab head
Michele Tinti
contact affiliationDundee University
contact emailm.tinti@dundee.ac.uk
dataset submitter
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Dataset FTP location
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