PXD050005-1

PXD050005 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Study of Potent inhibitors for CT5-3hTERT fibroblast cell line
Description	Data independent acquisition (DIA) mass spectrometry was used to study the potent inhibitors for cancer derived fibroblast cell line, CT5-3hTERT. The fibroblast spheroids were treated with 21 different tumor inhibitors to compare their effect in proteome in comparison to treated with DMSO.
HostingRepository	PRIDE
AnnounceDate	2024-08-10
AnnouncementXML	Submission_2024-08-10_13:00:40.174.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ujjwal Suwal
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-21 08:10:18	ID requested
⏵ 1	2024-08-10 13:00:40	announced
2	2024-10-22 06:54:32	announced	2024-10-22: Updated project metadata.

Publication List

Xia Z, Vermeulen S, Suwal U, Rappu P, Heino J, De Vuyst F, Dedeyne S, Hendrix A, Denys H, De Wever O, Cancer-associated fibroblasts mediate resistance to neoadjuvant therapy in breast cancer. Clin Transl Med, 14(7):e1779(2024) [pubmed]
10.1002/ctm2.1779;

Xia Z, Vermeulen S, Suwal U, Rappu P, Heino J, De Vuyst F, Dedeyne S, Hendrix A, Denys H, De Wever O, Cancer-associated fibroblasts mediate resistance to neoadjuvant therapy in breast cancer. Clin Transl Med, 14(7):e1779(2024) [pubmed]

10.1002/ctm2.1779;

Keyword List

submitter keyword: DIA mass spectrometry, Inhibitors,human fibroblasts, FAIMS-Orbitrap Lumos

submitter keyword: DIA mass spectrometry, Inhibitors,human fibroblasts, FAIMS-Orbitrap Lumos

Contact List

Jyrki Heino
contact affiliation	Department of Life Technologies and InFLAMES Research Flagship, University of Turku, FI-20014, Turku, Finland
contact email	jyrki.heino@utu.fi
lab head
Ujjwal Suwal
contact affiliation	University of Turku
contact email	ujjwal.suwal@utu.fi
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD050005
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD050005

PRIDE project URI

Repository Record List

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