PXD049999 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Integrated cellular response of the zebrafish (Danio rerio) heart in response to temperature change |
Description | Zebrafish are a tropical species of fish that inhabit streams that can fluctuate dramatically in temperature. In response to a decrease in temperature, the heart of zebrafish alters the structure of the myocardium and the expression of genes that code for proteins involved in contraction. Since very little is known about the processes supporting these changes in zebrafish, this study evaluated how the protein landscape of the ventricle changes with both an acute and a chronic decrease in temperature from 27oC to 20oC at multiple time points. this tested the hypothesis that a decrease in temperature would elicit changes in protein abundance and phosphorylation to maintain heart function. This study identified 1108, 1851, 1137, and 2325 phosphopeptides at each time point and 2052, 1656, 635, and 1530 proteins at each time point. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_07:02:02.403.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jared Shaftoe |
SpeciesList | scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Exploris 240 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-02-21 07:02:24 | ID requested | |
1 | 2024-10-15 05:38:18 | announced | |
⏵ 2 | 2024-10-22 07:02:02 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
submitter keyword: LC-MSMS, Phosphoproteomics, cold acclimation, heart,Zebrafish, Proteomics |
Contact List
Todd E. Gillis |
contact affiliation | Department of Integrative Biology, College of Biological Sciences, University of Guelph, Ontario, Canada |
contact email | tgillis@uoguelph.ca |
lab head | |
Jared Shaftoe |
contact affiliation | University of Guelph |
contact email | wjshaftoe@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD049999 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD049999
- Label: PRIDE project
- Name: Integrated cellular response of the zebrafish (Danio rerio) heart in response to temperature change