PXD049407-2

PXD049407 is an original dataset announced via ProteomeXchange.

Title	Selectivity of 2J2V for BET proteins in A549 cells
Description	Data independent acquisition (DIA) mass spectrometry was used to study the selectivity of 2J2V for BET proteins from A549 cells. BET proteins, BRD2, BRD3 and BRD4 were observed to be degraded the most by 2J2V in comparison to MZ1 or DMSO.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_07:00:51.695.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ujjwal Suwal
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-15 08:57:59	ID requested
1	2024-10-08 06:12:41	announced
⏵ 2	2024-10-22 07:00:52	announced	2024-10-22: Updated project metadata.

10.1039/D4SC03555K;

submitter keyword: BET proteins, DIA mass spectrometry, FAIMS-Orbitrap Lumos

Jyrki Heino
contact affiliation	Department of Life Technologies and InFLAMES Research Flagship, University of Turku, FI-20014, Turku, Finland
contact email	jyrki.heino@utu.fi
lab head
Ujjwal Suwal
contact affiliation	University of Turku
contact email	ujjwal.suwal@utu.fi
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD049407
     1. Label: PRIDE project
     2. Name: Selectivity of 2J2V for BET proteins in A549 cells