PXD049317-1

PXD049317 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations
Description	Submission contains data from proximity labeling combined to mass spectrometry (BioID) with protein of interest TPMT fused in-frame with BirA-R118G carboxylase expressed in HEK293 T-REx Flp-In cells. Proximity interacting proteins were captured with streptavidin sepharose, digested with trypsin and analyzed by LC-MS.
HostingRepository	MassIVE
AnnounceDate	2024-12-18
AnnouncementXML	Submission_2024-12-18_15:09:44.035.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jonathan St-Germain
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Oxidation; Deamidated; Acetyl
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-10 19:54:24	ID requested
⏵ 1	2024-12-18 15:09:44	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: HEK293 T-REx Flp-in, BioID, biotin, streptavidin, BirA, TPMT, LC-MS, , trypsin

submitter keyword: HEK293 T-REx Flp-in, BioID, biotin, streptavidin, BirA, TPMT, LC-MS, , trypsin

Contact List

Brian Raught
contact affiliation	Princess Margaret Cancer Centre
contact email	brian.raught@gmail.com
lab head
Jonathan St-Germain
contact affiliation	Princess Margaret Cancer Centre
contact email	jonstgermain@gmail.com
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000094061/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v07/MSV000094061/