PXD049299 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | A Proteomics Approach Identifies RREB1 as a Crucial Molecular Target of Imidazo–Pyrazole Treatment in SKMEL-28 Melanoma Cells |
Description | In a previous study, we described the biochemical properties of a newly synthesized group of imidazopyrazole compounds. In this paper, to improve our knowledge on the pharmacological properties of these chemical compounds, we carry out a differential proteomic analysis on a hu-man melanoma cell line treated with one of these imidazopyrazole derivatives. The results show the changes to Skmel28 melanoma cell line proteome induced by 24h, 48h and 72h of imidazopy-razole treatment. |
HostingRepository | PRIDE |
AnnounceDate | 2024-06-21 |
AnnouncementXML | Submission_2024-06-21_07:15:38.908.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Gabriela Coronel Vargas |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-02-09 06:01:04 | ID requested | |
⏵ 1 | 2024-06-21 07:15:39 | announced | |
Publication List
Keyword List
submitter keyword: imidazopyrazole |
cell growth inhibition |
differential proteomic analysis |
melanoma |
Contact List
Camillo Rosano |
contact affiliation | IRCCS Ospedale Policlinico San Martino, Genova, Italy |
contact email | camillo.rosano@hsanmartino.it |
lab head | |
Gabriela Coronel Vargas |
contact affiliation | University of Genova |
contact email | gabrielafernanda.coronelvargas@edu.unige.it |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD049299
- Label: PRIDE project
- Name: A Proteomics Approach Identifies RREB1 as a Crucial Molecular Target of Imidazo–Pyrazole Treatment in SKMEL-28 Melanoma Cells