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PXD049291-1
PXD049291 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comparison of Three Mitochondria Enrichment Methods for Glycoprotein/Glycopeptide Analysis |
| Description | Mitochondria proteome research has increased dramatically over the years owing to their implication in several diseases including cancer. With the aid of advanced technology such as mass spectrometry, over 1500 mitochondria proteins have been identified. Protein folding and function are significantly impacted by glycosylation; however, little is known about the glycosylation of mitochondria proteins. There are various techniques for isolating mitochondria, and the most suitable method is chosen based on the specific research objective. Hence, to identify a suitable protocol for comprehensive analysis of mitochondria glycoproteome, we compared three mitochondria enrichment methods. Our data showed that the differential centrifugation method yielded either a similar or a higher total number of mitochondria proteins/peptides compared to the two commercial kits, MITOISO2 (Sigma Aldrich) and Pierce (Thermo Scientific). |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-05-30 |
| AnnouncementXML | Submission_2026-05-30_14:12:20.277.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Judith Nwaiwu |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | unknown modification |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-02-09 02:33:50 | ID requested | |
| ⏵ 1 | 2026-05-30 14:12:20 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Mitochondria, Glycoprotein, HILIC enrichment |
Contact List
| Dr Yehia Mechref | |
|---|---|
| contact affiliation | Texas Tech University |
| contact email | yehia.mechref@ttu.edu |
| lab head | |
| Judith Nwaiwu | |
| contact affiliation | Texas Tech University |
| contact email | jnwaiwu@ttu.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v07/MSV000094048/ |
