PXD049067-1

PXD049067 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	TMT-based phosphoproteomics and proteomics analysis of the mouse sperm
Description	In this study, we conducted a comprehensive quantitative phosphoproteomic analysis of mouse epididymal sperm from different regions (caput, corpus, and cauda) to unveil the dynamics of protein phosphorylation during sperm maturation. And we performed phosphoproteomic analysis of ALK inhibitor 2 compound 18-treated and control sperm to gain further insights into the potential mechanisms by which TSSK2 regulates sperm motility.
HostingRepository	PRIDE
AnnounceDate	2024-10-17
AnnouncementXML	Submission_2024-10-17_03:54:02.493.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	xiangzheng zhang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-31 22:22:40	ID requested
⏵ 1	2024-10-17 03:54:03	announced

Publication List

Zhang X, Tu H, Zhou X, Wang B, Guo Y, Situ C, Qi Y, Li Y, Guo X, Quantitative Phosphoproteomic Profiling of Mouse Sperm Maturation in Epididymis Revealed Kinases Important for Sperm Motility. Mol Cell Proteomics, 23(8):100810(2024) [pubmed]
10.1016/j.mcpro.2024.100810;

Zhang X, Tu H, Zhou X, Wang B, Guo Y, Situ C, Qi Y, Li Y, Guo X, Quantitative Phosphoproteomic Profiling of Mouse Sperm Maturation in Epididymis Revealed Kinases Important for Sperm Motility. Mol Cell Proteomics, 23(8):100810(2024) [pubmed]

10.1016/j.mcpro.2024.100810;

Keyword List

submitter keyword: mouse, proteomics, TMT, sperm, phosphoproteomics

submitter keyword: mouse, proteomics, TMT, sperm, phosphoproteomics

Contact List

xuejiang guo
contact affiliation	State Key Laboratory of Reproductive Medicine and Offspring Health, Department of Histology and Embryology, Nanjing Medical University
contact email	guo_xuejiang@njmu.edu.cn
lab head
xiangzheng zhang
contact affiliation	nanjing medical university
contact email	zhangxiangzheng@njmu.edu.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD049067
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD049067

PRIDE project URI

Repository Record List

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