PXD048837 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome of cerebral thrombi retrieved in acute phase of stroke (ThrombiOMIC) |
| Description | The proteome of cerebral thrombi from patients recanalized by mechanical thrombectomy in an acute phase of stroke was carried out to determine biomarkers of stroke radio-clinical outcomes for stroke physicians (clinical outcome and mortality at 3 months, intracranial hemorrhagic transformation, etc.). Proteome of cerebral thrombi was also used to elucidate stroke physiopathology (paradoxical effect of glucose in acute phase of stroke) and evaluate recanalization treatments (intravenous thrombolysis by rt-PA and/or thrombectomy efficiency). ThrombiOMIC database was incremented by proteomic analyses of cerebral thrombi successfully retrieved from all consecutive stroke patients (n=59) with large vessel occlusion treated by mechanical thrombectomy in acute phase between October 2018 and August 2019 in the intensive care stroke unit of the University Hospital of Nice (France). |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-10-22 |
| AnnouncementXML | Submission_2024-10-22_06:28:02.204.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD048837 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Laurent SUISSA |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-01-24 07:20:02 | ID requested | |
| 1 | 2024-01-28 08:06:44 | announced | |
| ⏵ 2 | 2024-10-22 06:28:06 | announced | 2024-10-22: Updated project metadata. |
Publication List
| 10.1161/strokeaha.120.032129; |
| 10.6019/PXD048837; |
| 10.3390/metabo10120483; |
| Suissa L, Guigonis JM, Graslin F, Robinet-Borgomano E, Chau Y, Sedat J, Lindenthal S, Pourcher T, Combined Omic Analyzes of Cerebral Thrombi: A New Molecular Approach to Identify Cardioembolic Stroke Origin. Stroke, 52(9):2892-2901(2021) [pubmed] |
| Suissa L, Guigonis JM, Graslin F, Doche E, Osman O, Chau Y, Sedat J, Lindenthal S, Pourcher T, Metabolome of Cerebral Thrombi Reveals an Association between High Glycemia at Stroke Onset and Good Clinical Outcome. Metabolites, 10(12):(2020) [pubmed] |
Keyword List
| ProteomeXchange project tag: Cardiovascular (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project |
| submitter keyword: Human, LC-MSMS, Thrombus, Stroke, Proteomics |
Contact List
| SUISSA Laurent |
|---|
| contact affiliation | TIRO-MATOs, Faculté de Médecine, 28 Ave de Valombrose, 06107 Nice, France C2VN, Faculté de Médecine, Bd Jean Moulin, 13005 Marseille, France |
| contact email | laurent.suissa@ap-hm.fr |
| lab head | |
| Laurent SUISSA |
|---|
| contact affiliation | Stroke Unit - University Hospital of Marseille (France) C2VN - Aix-Marseille University (France) |
| contact email | laurent.suissa@ap-hm.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD048837
- Label: PRIDE project
- Name: Proteome of cerebral thrombi retrieved in acute phase of stroke (ThrombiOMIC)
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