PXD048633-2
PXD048633 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | TMT-labeled quantitative proteome analyses identify serum biomarkers in pregnant women with obstructive sleep apnea |
Description | Three healthy pregnant women without obstructive sleep apnea (OSA) (C), three pregnant women with mild OSA (O), and three pregnant women with moderate (MO) OSA were enrolled to identify serum diagnostic biomarkers-associated with the severity of OSA during pregnancy. Differentially expressed proteins (DEPs) among control (C), mild (O), and moderate (MO) OSA groups were identified. Bioinformatics analysis was conducted to discover the underlying functions, pathways and networks of the proteins. Furthermore, receiver operating characteristic curve (ROC) curve was used to assess the diagnostic value of the identified DEPs. A total of 141, 29, and 103 DEPs were identified among the three groups. C1R and A2M were identified as continuously upregulated proteins, and the levels of C1R and A2M were related with the severity of OSA. |
HostingRepository | iProX |
AnnounceDate | 2024-01-17 |
AnnouncementXML | Submission_2024-01-18_19:51:16.709.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Qiang Zhang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-01-17 03:03:58 | ID requested | |
1 | 2024-01-17 03:06:36 | announced | |
⏵ 2 | 2024-01-18 19:51:17 | announced | 2024-01-19: Update information. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: TMT-labeled |
Contact List
Li Xiao | |
---|---|
contact affiliation | Shengjing Hospital of China Medical University |
contact email | xiaoli@sj-hospital.org |
lab head | |
Qiang Zhang | |
contact affiliation | Shengjing Hospital of China Medical University |
contact email | cmusjzq2808@126.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |