PXD048625 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The cross-linking mass spectrometry (CX-MS) results of Human TIP60 complex (hTIP60) |
Description | Mammalian TIP60 is a multi-functional enzyme with histone acetylation and histone dimer exchange activities. It plays roles in diverse cellular processes including transcription, DNA repair, cell cycle control, and embryonic development. We performed structural study on human TIP60 complex with cryo-electron microscopy. The structural model of human TIP60 complex was built based on the high-resolution cryo-EM maps, assisted by cross-linking mass spectrometry (CX-MS) and AlphaFold2 prediction. |
HostingRepository | PRIDE |
AnnounceDate | 2024-07-11 |
AnnouncementXML | Submission_2024-07-10_19:55:13.270.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ke Chen |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-01-16 20:40:59 | ID requested | |
⏵ 1 | 2024-07-10 19:55:13 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Human, TIP60, CX-MS |
Contact List
Yanhui Xu |
contact affiliation | Fudan University Shanghai Cancer Center from China |
contact email | xuyh@fudan.edu.cn |
lab head | |
Ke Chen |
contact affiliation | no |
contact email | 17865196299@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD048625 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD048625
- Label: PRIDE project
- Name: The cross-linking mass spectrometry (CX-MS) results of Human TIP60 complex (hTIP60)