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PXD048625-1

PXD048625 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe cross-linking mass spectrometry (CX-MS) results of Human TIP60 complex (hTIP60)
DescriptionMammalian TIP60 is a multi-functional enzyme with histone acetylation and histone dimer exchange activities. It plays roles in diverse cellular processes including transcription, DNA repair, cell cycle control, and embryonic development. We performed structural study on human TIP60 complex with cryo-electron microscopy. The structural model of human TIP60 complex was built based on the high-resolution cryo-EM maps, assisted by cross-linking mass spectrometry (CX-MS) and AlphaFold2 prediction.
HostingRepositoryPRIDE
AnnounceDate2024-07-11
AnnouncementXMLSubmission_2024-07-10_19:55:13.270.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKe Chen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-01-16 20:40:59ID requested
12024-07-10 19:55:13announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, TIP60, CX-MS
Contact List
Yanhui Xu
contact affiliationFudan University Shanghai Cancer Center from China
contact emailxuyh@fudan.edu.cn
lab head
Ke Chen
contact affiliationno
contact email17865196299@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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