PXD048612-1

PXD048612 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Ho_BLM_TOP3A_RMI_BioID_P130_Velos_Elite
Description	This dataset consists of 25 raw MS files and associated peak lists and results files, acquired on a Thermo LTQ Velos Pro or Thermo Orbitrap Elite mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Edith Cheng. Affinity purifications and mass spectrometry acquisition was performed by Wade Dunham. Analysis was performed by Jennifer Ho, Wade Dunham, Edith Cheng, Cassandra Wong, Anne-Claude Gingras, and Grant Brown. The files are associated with a manuscript submitted for publication by Jung Jennifer Ho et al. The main goal of this paper was to profile the proximity interactome of BLM-TOP3A-RMI1-RMI2 (BTRR) complex to identify proteins that suppress recombination in DNA repair. This dataset identifies the importance of RAD54L2 for the recruitment of Bloom (BLM) helicase to promote non-crossover recombination. Grant W. Brown is the corresponding author of the manuscript (grant.brown@utoronto.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
HostingRepository	MassIVE
AnnounceDate	2024-12-20
AnnouncementXML	Submission_2024-12-20_09:38:01.131.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Gingras Lab
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	deamidated L-asparagine; deamidated L-glutamine; L-methionine sulfoxide
Instrument	LTQ Orbitrap Velos; LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-16 10:24:05	ID requested
⏵ 1	2024-12-20 09:38:01	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: BLM, TOP3A, RMI1, RMI2, BioID, Bloom helicase

submitter keyword: BLM, TOP3A, RMI1, RMI2, BioID, Bloom helicase

Contact List

Anne-Claude Gingras
contact affiliation	LTRI
contact email	gingras@lunenfeld.ca
lab head
Gingras Lab
contact affiliation	Samuel Lunenfeld Research Institute
contact email	gingras@mshri.on.ca
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000093876/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000093876/