PXD048533-1

PXD048533 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Comprehensive analysis of O-linked glycans on Notch receptors using mass spectrometry
Description	Notch signaling is essential for the development and homeostasis of multicellular organisms. Dysregulation of Notch signaling leads to several human diseases. Genetic and biochemical studies have shown that O-linked glycosylation on Notch receptors is essential for the transduction of Notch signaling. However, how O-linked glycans regulate the activity of Notch signaling is still unknown. To pursue this, we need to know the whole aspect of glycan modification on Notch. We performed mass spectrometric analysis of Notch1 and 3 to reveal O-glycosylation on each EGF repeat.
HostingRepository	jPOST
AnnounceDate	2025-01-14
AnnouncementXML	Submission_2025-01-13_07:00:04.122.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yohei Tsukamoto
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-14 10:16:58	ID requested
⏵ 1	2025-01-13 07:00:04	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Notch、O-Glycosilation

submitter keyword: Notch、O-Glycosilation

Contact List

Hideyuki Takeuchi
lab head
Yohei Tsukamoto
contact affiliation	Nagoya University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002462/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002462/