PXD048516-1

PXD048516 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Pla2g12b binding proteins in Zebrafish
Description	We injected larvae with the wild-type rescue plasmid described above, and performed co-immunoprecipitation and mass spectrometry (co-IP/MS) against the highly specific 3x-FLAG epitope linked to Pla2g12b. The top five most abundant proteins included the core components of the TRL assembly pathway (ApoB and the two Subunits of Mtp (Mttp and Pdi/P4hb)), as well as various chaperone proteins . These interactions suggest that Pla2g12b participates directly in TRL biogenesis, and may promote efficient channeling of lipids to ApoB by linking it more tightly to the transfer protein Mtp.
HostingRepository	MassIVE
AnnounceDate	2024-02-25
AnnouncementXML	Submission_2024-02-25_16:30:55.957.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sung Yun Jung
SpeciesList	scientific name: Danio rerio; common name: zebrafish; NCBI TaxID: 7955;
ModificationList	Oxidation
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-01-12 19:05:54	ID requested
⏵ 1	2024-02-25 16:30:56	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Pla2g12b

submitter keyword: Pla2g12b

Contact List

Steve Farber
contact affiliation	Johns Hopkins University
contact email	sfarber3@jhu.edu
lab head
Sung Yun Jung
contact affiliation	Baylor College of Medicine
contact email	syjung@bcm.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000093857/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000093857/