PXD048277 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Rebound after MAPK inhibitor withdrawal in pLGG cells |
Description | An in vitro MAPK inhibitor withdrawal rebound model was generated using the patient-derived, PXA-like cell line BT-40 (BRAFV600E, CDKN2Adel). Using this model, we investigated potential cellular intrinsic and extrinsic mechanisms involved in rebound growth in pLGG through multi-omics analysis (RNAseq, phospho-/proteomics). |
HostingRepository | PRIDE |
AnnounceDate | 2024-04-17 |
AnnouncementXML | Submission_2024-04-17_04:07:05.724.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Daniela Kocher |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; acetylated residue; monohydroxylated residue; deamidated residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-01-05 08:41:19 | ID requested | |
⏵ 1 | 2024-04-17 04:07:06 | announced | |
Publication List
Keyword List
submitter keyword: proteomic analysis, phosphoproteomic analysis, treatment withdrawal, MAPK inhibitor,pediatric low-grade glioma |
Contact List
Romain Sigaud |
contact affiliation | Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany German Cancer Research Center (DKFZ), Clinical Cooperation Unit Pediatric Oncology , Heidelberg, Germany |
contact email | r.sigaud@kitz-heidelberg.de |
lab head | |
Daniela Kocher |
contact affiliation | Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany |
contact email | d.kocher@kitz-heidelberg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD048277
- Label: PRIDE project
- Name: Rebound after MAPK inhibitor withdrawal in pLGG cells