PXD048151-2
PXD048151 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | EIF3H-interactome in Colorectal Cancer cell line (HCT116) |
Description | To elucidate the molecular mechanism and search for EIF3H substrate(s) of EIF3H-mediated CRC progression, we performed immune-affinity purification and resolved the binding partners utilizing mass spectrometry. HCT116 cells transfected with empty vector or Flag-tagged EIF3H and then immunoprecipitated using anti-Flag M2 beads.The purified EIF3H protein complex was subjected to mass spectrometry analysis. |
HostingRepository | iProX |
AnnounceDate | 2023-12-26 |
AnnouncementXML | Submission_2024-03-26_00:01:19.239.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Huilin Jin |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-12-27 18:04:45 | ID requested | |
1 | 2023-12-27 18:05:14 | announced | |
⏵ 2 | 2024-03-26 00:01:20 | announced | 2024-03-26: Update information. |
Publication List
Jin H, Huang X, Pan Q, Ma N, Xie X, Wei Y, Yu F, Wen W, Zhang B, Zhang P, Chen X, Wang J, Liu RY, Lin J, Meng X, Lee MH, The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression. Nat Commun, 15(1):2551(2024) [pubmed] |
Keyword List
submitter keyword: EIF3H-interactome, Colorectal Cancer cell line, HCT116 |
Contact List
Monghong Lee | |
---|---|
contact affiliation | The Sixth Affiliated Hospital, Sun Yat-sen University |
contact email | limh33@mail.sysu.edu.cn |
lab head | |
Huilin Jin | |
contact affiliation | The Sixth Affiliated Hospital, Sun Yat-sen University |
contact email | jinhlin3@mail.sysu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |