PXD048092 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Effect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome |
Description | The exact molecular mechanisms by which PTGFRN influences cancer progression are still unknown. Our laboratory set out to investigate how PTGFRN knockdown affected the expression of other proteins. We also carried out co-immunoprecipitation experiments using a monoclonal anti-PTGFRN antibody. We employed mass spectrometry-based proteomics for both experiments to identify proteins that were associated with PTGFRN. |
HostingRepository | PRIDE |
AnnounceDate | 2024-06-22 |
AnnouncementXML | Submission_2024-06-22_09:31:32.321.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mehari Weldemariam |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-12-22 17:03:24 | ID requested | |
⏵ 1 | 2024-06-22 09:31:33 | announced | |
Publication List
Marquez J, Weldemariam MM, Dong J, Hayashi J, Kane MA, Serrero G, Effect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome. ACS Omega, 9(12):14381-14387(2024) [pubmed] |
10.1021/acsomega.4c00042; |
Keyword List
submitter keyword: A431, PTGFRN, mass spectrometry, Interactome,Proteome, co-immunoprecipitate |
Contact List
Maureen A. Kane |
contact affiliation | Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201, United States of Americ |
contact email | mkane@rx.umaryland.edu |
lab head | |
Mehari Weldemariam |
contact affiliation | University of Maryland Baltimore |
contact email | mweldemariam@rx.umaryland.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD048092 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD048092
- Label: PRIDE project
- Name: Effect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome