PXD047998 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa |
Description | To delineate sodium valproate (VPA) molecular effects underlying mitigation of skin fibrosis in RDEB mice, mass spectrometry-based expression proteomics was performed on protein extracts from back skin of 16 weeks-old VPA-treated RDEB mice, vehicle-treated RDEB mice and WT littermates. |
HostingRepository | PRIDE |
AnnounceDate | 2024-08-31 |
AnnouncementXML | Submission_2024-08-31_03:29:49.107.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Joern Dengjel |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-12-20 05:14:04 | ID requested | |
⏵ 1 | 2024-08-31 03:29:49 | announced | |
2 | 2024-10-22 06:57:33 | announced | 2024-10-22: Updated project metadata. |
Publication List
Primerano A, De Domenico E, Cianfarani F, De Luca N, Floriddia G, Teson M, Cristofoletti C, Cardarelli S, Scaglione GL, Baldini E, Cangelosi D, Uva P, Reinoso S, á, nchez JF, Roubaty C, Dengjel J, Nystr, ö, m A, Mastroeni S, Ulisse S, Castiglia D, Odorisio T, epidermolysis bullosa. Br J Dermatol, 191(4):568-579(2024) [pubmed] |
10.1093/bjd/ljae225; |
Keyword List
submitter keyword: LC-MSMS,mouse, sodium valproate, RDEB, fibrosis |
Contact List
Joern Dengjel |
contact affiliation | Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 |
contact email | joern.dengjel@unifr.ch |
lab head | |
Joern Dengjel |
contact affiliation | University of Fribourg |
contact email | joern.dengjel@medizin.uni-freiburg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD047998 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047998
- Label: PRIDE project
- Name: Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa