PXD047970-1

PXD047970 is an original dataset announced via ProteomeXchange.

Title	SART1 modulates Poly-(ADP-Ribose) accumulation and PARP1 chromatin localization
Description	Protein modular domains mediate signal transduction events in all living cells and play a significant role in the cellular responses to the environment. The BRCT domain is a versatile protein modular domain that is a key integrator of signals in the DNA damage response. To identify components of the proteome that connect and integrate signals between the DNA damage response and other cellular functions, we generated the protein-protein interaction network for the BRCT domain of PARP1 using tandem affinity purification coupled to mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2024-11-04
AnnouncementXML	Submission_2024-11-04_09:02:35.326.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD047970
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Nicholas Woods
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-19 15:35:13	ID requested
⏵ 1	2024-11-04 09:02:35	announced

10.1016/J.ISCI.2024.111252;

10.6019/PXD047970;

submitter keyword: SART1, PARP1, BRCT domain, DNA damage response

Alvaro N. Monteiro, Ph.D.
contact affiliation	Cancer Epidemiology Program, Division of Population Sciences, H. Lee Moffitt Cancer Center
contact email	alvaro.monteiro@moffitt.org
lab head
Nicholas Woods
contact affiliation	University of Nebraska Medical Center - Eppley Institute for Research in Cancer
contact email	nicholas.woods@unmc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/11/PXD047970

PRIDE project URI

• PRIDE
  1. PXD047970
     1. Label: PRIDE project
     2. Name: SART1 modulates Poly-(ADP-Ribose) accumulation and PARP1 chromatin localization