PXD047888-1
PXD047888 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | USP18-mediated NCOA4 deISGylation and ferroptosis inhibition drives targeted therapy resistance in hepatocellular carcinoma |
| Description | To elucidate the principal downstream mediator responsible for USP18-mediated Sorafenib resistance in HCC, we conducted cluster analysis on the differential protein expression based on the whole-proteome analysis of HepG2 cells with or without overexpression of USP18 (HepG2-USP18-OE vs. HepG2-Ctrl), we identified 47 commonly downregulated proteins and 31 upregulated proteins . |
| HostingRepository | iProX |
| AnnounceDate | 2023-12-17 |
| AnnouncementXML | Submission_2023-12-17_20:26:23.341.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shengtao Ye |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-12-17 20:26:04 | ID requested | |
| ⏵ 1 | 2023-12-17 20:26:23 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: USP18, deISGylation, ferroptosis, targeted therapy resistance, HCC. |
Contact List
| Hao Zhang | |
|---|---|
| contact affiliation | China Pharmaceutical University |
| contact email | zhanghao@cpu.edu.cn |
| lab head | |
| Shengtao Ye | |
| contact affiliation | China Pharmaceutical University |
| contact email | yst_cpu961223@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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