PXD047542 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Inhalation of ACE2-expressing lung spheroid cell exosomes provides prophylactic protection against SARS-CoV-2 |
Description | We demonstrated that lung spheroid cell derived exosomes (LSC-Exo) carry the parental cell’s ACE2 that are able to target lung, intercept SARS-CoV-2 entry, confer protection against SARS-CoV-2 infection. This LSC-Exo prophylaxis paradigm would not be limited by viral evolution, showing great potential for emerged SARS-CoV-2 variants, including those that are yet to emerge. |
HostingRepository | PRIDE |
AnnounceDate | 2024-01-13 |
AnnouncementXML | Submission_2024-01-13_06:20:19.575.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD047542 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Zhenzhen Wang |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-12-05 11:51:46 | ID requested | |
⏵ 1 | 2024-01-13 06:20:19 | announced | |
Publication List
Keyword List
submitter keyword: LC-MS,exosomes |
Contact List
Zhenzhen Wang |
contact affiliation | South China University of Technology |
contact email | zwang@scut.edu.cn |
lab head | |
Zhenzhen Wang |
contact affiliation | (+86)19924307306 |
contact email | zwang@scut.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD047542 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047542
- Label: PRIDE project
- Name: Inhalation of ACE2-expressing lung spheroid cell exosomes provides prophylactic protection against SARS-CoV-2