PXD047329-1
PXD047329 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Chondrodysplasia-inducing COL2A1 p.Gly1170Ser causes an ER storage defect without associated unfolded protein response in a human cartilage model |
Description | 10-plex TMT dataset generated by immunoprecipitation of epitope-tagged COL2A1 constructs along with DSP-crosslinked interactors. This experiment allows for quantitative comparison of wild-type and Gly1170Ser COL2A1 interactomes in HT-1080 cells transiently transfected with COL2A1 under a constitutive promoter. Negative control samples are untransfected HT-1080 cells, used to identify high-confidence collagen-II interactors from non-specific binders. |
HostingRepository | MassIVE |
AnnounceDate | 2023-11-28 |
AnnouncementXML | Submission_2023-11-28_10:38:19.862.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Richard Schiavoni |
SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
ModificationList | TMT6plex; Oxidation; Acetyl; Methyl |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-11-28 05:55:54 | ID requested | |
⏵ 1 | 2023-11-28 10:38:20 | announced |
Publication List
no publication |
Keyword List
submitter keyword: COL2A1, Quantitative Proteomics, TMT Labeling, |
Contact List
Matthew Shoulders | |
---|---|
contact affiliation | MIT |
contact email | mshoulde@mit.edu |
lab head | |
Richard Schiavoni | |
contact affiliation | MIT |
contact email | rpschiav@mit.edu |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000093517/ |