PXD047251-2
PXD047251 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Generation of a deep mouse brain spectral library for transmembrane proteome profiling in mental disease models |
| Description | The establishment of a high-quality mouse brain transmembrane proteins spectral library enables in-depth profiling of the proteins across multiple brain regions. DIA data analysis, combining different search pipeline based on the spectral library, discovered a new GPCR regulator which was associated with depression verified via in vivo tests. This library represents a valuable resource that has the potential to discover the putative drug targets. |
| HostingRepository | iProX |
| AnnounceDate | 2023-11-26 |
| AnnouncementXML | Submission_2024-05-15_01:18:09.617.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shanshan Li |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-11-26 22:34:26 | ID requested | |
| 1 | 2023-11-26 22:34:59 | announced | |
| ⏵ 2 | 2024-05-15 01:18:10 | announced | 2024-05-15: Update information. |
Publication List
Keyword List
| submitter keyword: mouse brain, spectral library, transmembrane proteome, data-independent acquisition, mental disorder |
Contact List
| Wenqing Shui | |
|---|---|
| contact affiliation | iHuman Institute, ShanghaiTech University |
| contact email | shuiwq@shanghaitech.edu.cn |
| lab head | |
| Shanshan Li | |
| contact affiliation | ShanghaiTech University |
| contact email | lishsh@shanghaitech.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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