PXD047079-1
PXD047079 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Spermidine Deficiency Promotes the Activation of RIPK1 to Mediate Diabetic Onset and Progression |
| Description | We identify spermidine targeting RIPK1, a key regulator of cell death and inflammation, by mediating a new type of posttranslational modification, named acetylhypusination, to inhibit RIPK1-mediated inflammation and cell death. |
| HostingRepository | iProX |
| AnnounceDate | 2023-11-18 |
| AnnouncementXML | Submission_2024-09-23_23:36:51.191.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Bing Shan |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | hypusine |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-11-19 22:39:17 | ID requested | |
| ⏵ 1 | 2024-09-23 23:36:51 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: spermidine, RIPK1 |
Contact List
| Junying Yuan | |
|---|---|
| contact affiliation | Shanghai Institute of Organic Chemistry, CAS |
| contact email | junying_yuan@sioc.ac.cn |
| lab head | |
| Bing Shan | |
| contact affiliation | Shanghai Institute of Organic Chemistry, CAS |
| contact email | shanbing@sioc.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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