PXD046785 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | TOPOVIBL∆C25 mouse protein purification from insect cells |
Description | The project aims at studying in vitro the TOPOVIBL∆C25 protein. This protein is essential to the formation of DNA double strand breaks, which initiates homologous recombination in meiosis in the mice. We set up a purification procedure of the recombinant TOPOVIBL∆C25 protein expressed in insect cells, which was validated using MS/MS approaches. |
HostingRepository | PRIDE |
AnnounceDate | 2024-07-09 |
AnnouncementXML | Submission_2024-07-08_23:29:51.334.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD046785 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Functional Proteomics Platform FPP |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-11-08 07:26:50 | ID requested | |
⏵ 1 | 2024-07-08 23:29:52 | announced | |
Publication List
Diagouraga B, Tambones I, Carivenc C, Bechara C, Nadal M, de Massy B, le Maire A, Robert T, The TOPOVIBL meiotic DSB formation protein: new insights from its biochemical and structural characterization. Nucleic Acids Res, 52(15):8930-8946(2024) [pubmed] |
10.6019/PXD046785; |
10.1093/nar/gkae587; |
Keyword List
submitter keyword: MS/MS,Mouse, Insect cells, testes |
Contact List
Thomas Robert |
contact affiliation | Centre de Biologie Structurale (CBS), CNRS, INSERM, Univ Montpellier, 34090 Montpellier, France |
contact email | thomas.robert@cbs.cnrs.fr |
lab head | |
Functional Proteomics Platform FPP |
contact affiliation | FPP CNRS |
contact email | contact@fpp.cnrs.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD046785
- Label: PRIDE project
- Name: TOPOVIBL∆C25 mouse protein purification from insect cells