⮝ Full datasets listing
PXD046769-1
PXD046769 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics of PCa under antiandrogen treatment |
| Description | In this study, 33 PCa and 10 control samples were collected, including 9 paired samples, and 4D DIA-based proteomics was employed to scrutinize the proteome alterations in PCa patients. Several potential diagnostic biomarkers were identified at both mRNA and protein levels. Furthermore, to analyze the effect of antiandrogens on proteome of PCa, we divided PCa samples into two groups, treated with bicalutamide and non-treated group. Sixty-eight up-regulated and 59 down-regulated proteins upon bicalutamide treatment were found as significantly differential proteins. In addition, proteomics profiles of PCa cells under enzalutamide treatment were analyzed. |
| HostingRepository | iProX |
| AnnounceDate | 2023-11-08 |
| AnnouncementXML | Submission_2026-07-12_17:41:55.271.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shan Wang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480; timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-11-07 23:49:45 | ID requested | |
| ⏵ 1 | 2026-07-12 17:41:55 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Proteomics, Prostate cancer, antiandrogen, diagnostic biomarker |
Contact List
| Shan Wang | |
|---|---|
| contact affiliation | Guangxi Medical University Cancer Hospital |
| contact email | sinoshanw@163.com |
| lab head | |
| Shan Wang | |
| contact affiliation | Guangxi Medical University Cancer Hospital |
| contact email | sinoshanw@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
