PXD046759 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Role of the Yersinia pestis Phospholipase D (Ymt) in the Initial Aggregation Step of Biofilm Formation in the Flea |
Description | Transmission of Yersinia pestis by fleas depends on the formation of condensed bacterial aggregates embedded within a gel-like matrix that localize to the proventricular valve in the flea foregut and interfere with normal blood feeding.The matrix of the bacterial aggregates is complex,containing large amounts of protein and lipid (particularly cholesterol) derived from the flea's blood meal. The goal of this study was to biochemically characterize the EPS of the Y. pestis aggregates that form after infection and to identify factors required for this initial stage of biofilm formation. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:38:17.105.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yixiang Zhang |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Xenopsylla cheopis; NCBI TaxID: 163159; scientific name: Yersinia pestis CO92; NCBI TaxID: 214092; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-11-07 14:39:32 | ID requested | |
1 | 2024-05-06 15:16:34 | announced | |
⏵ 2 | 2024-10-22 06:38:17 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: flea, biofilm,Yersinia pestis |
Contact List
B Joseph Hinnebusch |
contact affiliation | Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. |
contact email | jhinnebusch51@gmail.com |
lab head | |
Yixiang Zhang |
contact affiliation | RML/NIAID/NIH |
contact email | alexzhangyx@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD046759 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD046759
- Label: PRIDE project
- Name: Role of the Yersinia pestis Phospholipase D (Ymt) in the Initial Aggregation Step of Biofilm Formation in the Flea