PXD046748-1

PXD046748 is an original dataset announced via ProteomeXchange.

Title	Histone modification profile of Pristionchus pacificus
Description	Pristionchus pacificus has emerged as a valuable model system for comparative and evolutionary-developmental biology (evo-devo) studies alongside the classic model nematode C. elegans. Previous studies have identified a lack of conservation of genetic networks underlying conserved traits, referred to as developmental systems drift. However, the conservation – or lack thereof – of epigenetic pathways which regulate development have not been investigated. In the manuscript associated with this study, we present an “epigenetic toolkit” for P. pacificus and C. elegans to compare and contrast epigenetic pathways. Assembly of this toolkit was done by identifying orthologous genes, including the “writers” and “erasers” of histone modifications. To complement this evolutionary approach, here we produce a data set of the suite of histone modifications present in P. pacificus.
HostingRepository	PRIDE
AnnounceDate	2024-03-14
AnnouncementXML	Submission_2024-03-14_02:23:13.540.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mirita Franz-Wachtel
SpeciesList	scientific name: Nematoda; NCBI TaxID: NCBITaxon:6231; scientific name: Pristionchus pacificus; NCBI TaxID: 54126;
ModificationList	monomethylated residue; ubiquitinylated lysine; crotonylated L-lysine; trimethylated residue; phosphorylated residue; acetylated residue; dimethylated residue; N6-butanoyl-L-lysine; iodoacetamide derivatized residue; N6-((3R)-3-hydroxybutanoyl)-L-lysine; O-(N-acetylamino)hexosyl-L-serine; O-(N-acetylamino)hexosyl-L-threonine; N6-propanoyl-L-lysine
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-07 07:34:44	ID requested
⏵ 1	2024-03-14 02:23:13	announced
2	2024-10-22 06:33:23	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: epigenetics, P. pacificus,histone modifications, nematodes

Michael S. Werner
contact affiliation	University of Utah, School of Biological Sciences Salt Lake City, Utah, U.S.A.
contact email	michael.werner@utah.edu
lab head
Mirita Franz-Wachtel
contact affiliation	Proteome Center Tuebingen
contact email	mirita.franz@uni-tuebingen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD046748

PRIDE project URI

• PRIDE
  1. PXD046748
     1. Label: PRIDE project
     2. Name: Histone modification profile of Pristionchus pacificus