PXD046694-1

PXD046694 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Egg MVBs elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization
Description	Abstract: Mitochondria are maternally inherited, but the mechanisms underlying paternal mitochondrial elimination (PME) after fertilization are far less clear. In Drosophila, special egg-derived multivesicular bodies (MVBs) promote PME. To uncover the cellular degradative pathway mediated by the MVBs to degrade the sperm mitochondrial derivative, we isolated these vesicles from early fertilized eggs, using a subcellular fractionation procedure and subjected them to mass spectrometry (MS) analysis.
HostingRepository	MassIVE
AnnounceDate	2024-05-26
AnnouncementXML	Submission_2024-05-26_05:50:20.576.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yishai Levin
SpeciesList	scientific name: Drosophila melanogaster; common name: fruit fly; NCBI TaxID: 7227;
ModificationList	Deamidated; Oxidation; Carbamidomethyl
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-06 02:35:03	ID requested
⏵ 1	2024-05-26 05:50:20	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Drosophila, MVB, multivesicular bodies

submitter keyword: Drosophila, MVB, multivesicular bodies

Contact List

Eli Arama
contact affiliation	Weizmann Institute of Science
contact email	eli.arama@weizmann.ac.il
lab head
Yishai Levin
contact affiliation	Weizmann Institute of Science
contact email	yishai.levin@weizmann.ac.il
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000093306/