PXD046661 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Characterize proteome-wide changes in protein abundance and ubiquitination during glucose starvation in wild-type and HOIL-1mut AC16 cardiomyocytesCharacterize proteome-wide changes in protein abundance and ubiquitination during glucose starvation in wild-type and HOIL-1mut AC16 cardiomyocytes |
| Description | The cells expressing a truncated form of the E3 ubiquitin ligase HOIL-1 are hypersensitive to lethal metabolic stress. We hypothesize that alterations in ubiquitination or abundance of key substrates constitutes a mechanistic underpinning of this phenotype. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-13 |
| AnnouncementXML | Submission_2026-03-12_20:11:26.505.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zhiping Wu |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-11-03 15:29:24 | ID requested | |
| ⏵ 1 | 2026-03-12 20:11:27 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: TMTpro,HOIl-1, ubiquitination |
Contact List
| Junmin Peng |
|---|
| contact affiliation | St. Jude Children's Research Hospital |
| contact email | junmin.peng@stjude.org |
| lab head | |
| Zhiping Wu |
|---|
| contact affiliation | St. Jude Children's Research Hospital |
| contact email | zhiping.wu@stjude.org |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD046661 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD046661
- Label: PRIDE project
- Name: Characterize proteome-wide changes in protein abundance and ubiquitination during glucose starvation in wild-type and HOIL-1mut AC16 cardiomyocytesCharacterize proteome-wide changes in protein abundance and ubiquitination during glucose starvation in wild-type and HOIL-1mut AC16 cardiomyocytes
