PXD046579-1

PXD046579 is an original dataset announced via ProteomeXchange.

Title	The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
Description	A quantitative phosphoproteomic study was performed on mouse embryonic fibroblasts (MEF) knocked-out of IRE1 protein and re rexpressin it culturen in 25mM glucose media. The chosen experimental strategy was to perform phosphopeptide enrichment associated with multiplex protein identification and quantification by LC-MSMS on a high-resolution mass spectrometer using tandem mass tag (TMT9; Thermo Fisher Scientific) technology and High- Select Fe-NTA Phosphopeptide Enrichment Kit (Thermo Fisher Scientific).
HostingRepository	PRIDE
AnnounceDate	2023-12-08
AnnouncementXML	Submission_2023-12-08_07:17:38.088.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD046579
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Amado Carreras
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-01 07:22:22	ID requested
⏵ 1	2023-12-08 07:17:38	announced
2	2024-10-22 06:17:02	announced	2024-10-22: Updated project metadata.

10.6019/PXD046579;

10.1016/j.celrep.2023.113540;

Carreras-Sureda A, Zhang X, Laubry L, Brunetti J, Koenig S, Wang X, Castelbou C, Hetz C, Liu Y, Frieden M, Demaurex N, The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation. Cell Rep, 42(12):113540(2023) [pubmed]

submitter keyword: IRE1, SOCE,ER stress, STIM1

Amado Carreras Sureda
contact affiliation	Department of Cellular Physiology and Metabolism, Medical University center, Universitiy of Geneva, Geneva, Switzerland
contact email	Amado.CarrerasSureda@unige.ch
lab head
Amado Carreras
contact affiliation	University of Geneva
contact email	amado.carrerassureda@unige.ch
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD046579
     1. Label: PRIDE project
     2. Name: The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation