PXD046579

PXD046579 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation
Description	A quantitative phosphoproteomic study was performed on mouse embryonic fibroblasts (MEF) knocked-out of IRE1 protein and re rexpressin it culturen in 25mM glucose media. The chosen experimental strategy was to perform phosphopeptide enrichment associated with multiplex protein identification and quantification by LC-MSMS on a high-resolution mass spectrometer using tandem mass tag (TMT9; Thermo Fisher Scientific) technology and High- Select Fe-NTA Phosphopeptide Enrichment Kit (Thermo Fisher Scientific).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:17:01.197.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD046579
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Amado Carreras
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-01 07:22:22	ID requested
1	2023-12-08 07:17:38	announced
⏵ 2	2024-10-22 06:17:02	announced	2024-10-22: Updated project metadata.

Publication List

10.6019/PXD046579;
10.1016/j.celrep.2023.113540;
Carreras-Sureda A, Zhang X, Laubry L, Brunetti J, Koenig S, Wang X, Castelbou C, Hetz C, Liu Y, Frieden M, Demaurex N, The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation. Cell Rep, 42(12):113540(2023) [pubmed]

10.6019/PXD046579;

10.1016/j.celrep.2023.113540;

Carreras-Sureda A, Zhang X, Laubry L, Brunetti J, Koenig S, Wang X, Castelbou C, Hetz C, Liu Y, Frieden M, Demaurex N, The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation. Cell Rep, 42(12):113540(2023) [pubmed]

Keyword List

submitter keyword: IRE1, SOCE,ER stress, STIM1

submitter keyword: IRE1, SOCE,ER stress, STIM1

Contact List

Amado Carreras Sureda
contact affiliation	Department of Cellular Physiology and Metabolism, Medical University center, Universitiy of Geneva, Geneva, Switzerland
contact email	Amado.CarrerasSureda@unige.ch
lab head
Amado Carreras
contact affiliation	University of Geneva
contact email	amado.carrerassureda@unige.ch
dataset submitter

Full Dataset Link List

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PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD046579

PRIDE project URI

Repository Record List

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