PXD046427-1

PXD046427 is an original dataset announced via ProteomeXchange.

Title	HEK293T 15xGly/99xGly soluble quantitative proteomics
Description	In order to determine the protein composition of polyglycine aggregates, clonal HEK293T cell lines harboring doxycycline (DOX)-suppressible 15xGly-eGFP-3xHA or 99xGly-eGFP-3xHA constructs were grown either in standard media for 14 days (induction of transgene) or maintained in DOX (suppression of transgene).
HostingRepository	PRIDE
AnnounceDate	2025-07-18
AnnouncementXML	Submission_2025-07-17_18:06:08.647.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Raghu Chivukula
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-26 10:03:06	ID requested
⏵ 1	2025-07-17 18:06:09	announced

10.1126/SCIENCE.ADO2403;

submitter keyword: GGC repeat,polyglycine

Raghu R.
contact affiliation	Massachusetts General Hospital Harvard Medical School
contact email	rchivukula@mgh.harvard.edu
lab head
Raghu Chivukula
contact affiliation	Massachusetts General Hospital Harvard Medical School
contact email	rchivukula@mgh.harvard.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD046427

PRIDE project URI

• PRIDE
  1. PXD046427
     1. Label: PRIDE project
     2. Name: HEK293T 15xGly/99xGly soluble quantitative proteomics