PXD046408-1

PXD046408 is an original dataset announced via ProteomeXchange.

Title	Multi-omic Analyses Identified a Novel Biomarker in Abnormal Uterine Bleeding with Ovulatory Dysfunction
Description	This study used multi-omic analyses to reveal the mechanisms underlying the progression of abnormal uterine bleeding with ovulatory dysfunction (AUB-O) to AUB with atypical hyperplasia/malignancy (AUB-M), discovering that SFRP4 influences human endometrial epithelial cells (hEECs) apoptosis, migration, invasion, proliferation, and colony formation via the Wnt pathway.
HostingRepository	iProX
AnnounceDate	2023-10-26
AnnouncementXML	Submission_2023-10-26_00:11:31.842.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yunxiu Zhao
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-26 00:08:25	ID requested
⏵ 1	2023-10-26 00:11:32	announced

Dataset with its publication pending

submitter keyword: multi-omic analyses, abnormal uterine bleeding with ovulatory dysfunction (AUB-O), abnormal uterine bleeding with atypical hyperplasia/malignancy (AUB-M), secreted frizzled-related protein 4 (SFRP4), Wnt pathway

Jianhong Zhou
contact affiliation	Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine
contact email	zhoujh1117@zju.edu.cn
lab head
Yunxiu Zhao
contact affiliation	Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine
contact email	12118532@zju.edu.cn
dataset submitter

iProX dataset URI