PXD046305-2
PXD046305 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Lipidomics: The brain-blood-gut axis is associated with variability in stress sensitivity in mice |
| Description | Chronic stress can have lasting effects on some individuals, while there are other individuals who exhibit both susceptibility and resistance to the same stressor [43]. During stressful stimuli, resistant individuals exhibited weaker depression-like behaviors, while susceptible individuals showed increased depression-like behaviors. However, the causal relationship between individual behavioral differences and susceptibility and resistance is unclear. Here, we first distinguish between HPSM and LSPM behaviorally. Since gut research is also a new avenue for exploring behavioral changes, We found that susceptible and resistant mice are g-Desulfovibrio/g-Mycoplasma and its metabolite (tetrahydrocortisone/4,4-dimethyl-5alpha-cholinester-8,14, 24-triene-3 There was also a significant difference in the amount of beta-ol. Because gut bacteria are far from the brain, which has a tight blood-brain barrier. |
| HostingRepository | iProX |
| AnnounceDate | 2023-10-21 |
| AnnouncementXML | Submission_2023-12-11_00:10:00.109.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | ChaoShuai Shang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-10-22 21:01:26 | ID requested | |
| 1 | 2023-12-10 20:14:56 | announced | |
| ⏵ 2 | 2023-12-11 00:10:00 | announced | 2023-12-11: Update information. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: brain–blood–gut axis, stress sensitivity |
Contact List
| Yajun Qiao | |
|---|---|
| contact affiliation | Northwest Institute of Plateau Biology, Chinese Academy of Sciences |
| contact email | 879316810@qq.com |
| lab head | |
| ChaoShuai Shang | |
| contact affiliation | Northwest Institute of Plateau Biology, Chinese Academy of Sciences |
| contact email | shchaoshuai@foxmail.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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