PXD046278-1

PXD046278 is an original dataset announced via ProteomeXchange.

Title	Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds
Description	isoTOP-ABPP performed for a small library of cysteine-reactive compounds to assess cysteine ligandability of viral and host proteins towards these compounds.
HostingRepository	PRIDE
AnnounceDate	2024-10-24
AnnouncementXML	Submission_2024-10-24_12:51:00.403.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Flowreen Shikwana
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	biotinylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-20 21:05:59	ID requested
⏵ 1	2024-10-24 12:51:00	announced

10.1038/S41589-024-01760-9;

submitter keyword: isoTOP-ABPP

SARS-CoV-2

cysteine-reactive compounds

proteostasis

Orbitrap Eclipse: SP3

FAIMS

Keriann Marie Backus
contact affiliation	Biological Chemistry, UCLA, United States
contact email	kbackus@mednet.ucla.edu
lab head
Flowreen Shikwana
contact affiliation	UCLA
contact email	flowreen.shikwana@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD046278

PRIDE project URI

• PRIDE
  1. PXD046278
     1. Label: PRIDE project
     2. Name: Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds