PXD046259-1

PXD046259 is an original dataset announced via ProteomeXchange.

Title	Ejection of mitochondria and TNF-α activation mediate hypertonicity-induced adipocytes dedifferentiation
Description	Adipocyte extracellular vesicles and particles (EVs) proteomic profiling. In this study, we focus on the EVs proteomes changes induced by hypertonicity in 3T3-L1 and differentiated adipocytes. The source cells were cultured with isotonic/hypertonic medium for 48 hours, and EVs were isolated from the conditional medium using sequential ultracentrifugation. A label-free MS strategy was employed to achieve proteome identification and quantification.
HostingRepository	iProX
AnnounceDate	2023-10-20
AnnouncementXML	Submission_2023-10-20_05:02:18.342.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	ZHANG Liang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-20 05:00:24	ID requested
⏵ 1	2023-10-20 05:02:18	announced
2	2024-02-22 19:51:09	announced	2024-02-23: Update information.

Dataset with its publication pending

submitter keyword: adipocyte, hypertonicity, EVs, mitochondria

ZHANG Liang
contact affiliation	City Univeristy of Hong Kong
contact email	liangzhang.28@cityu.edu.hk
lab head
ZHANG Liang
contact affiliation	City University of Hong Kong
contact email	liangzhang.28@cityu.edu.hk
dataset submitter

iProX dataset URI